Sure - you can put the HTML on top of the canvas by using absolute positioning.

http://jsfiddle.net/stevendwood/5sSWj/

You cannot have HTML in the canvas. But supposing that the canvas and the HTML use the same coordinates then you can use top and left to position elements in the canvas using the same offsets as you draw with.

#picture {

    position: relative;

}



.blob, .blob1, .blob2 {

    position: absolute;

    width: 30px;

    height: 30px;

    border-radius: 20px;

    background-color: green;

    border: 2px solid #ccc;

}





var canvas = document.querySelector('canvas'),

    context = canvas.getContext('2d');



context.beginPath();

context.moveTo(100, 150);

context.lineTo(350, 50);

context.stroke();

And the HTML...

<div id=picture>

    <canvas id=canvas width=500 height=500>

    </canvas>

    <div class=blob1></div>

    <div class=blob2></div>

</div>

In this fetching example you can connect two positioned divs with a line drawn on a canvas element that is underneath them.