Currently using: https://github.com/felixge/node-mysql

I have the following code:

var connection = mysql.createConnection({

    host     : 'localhost',

    user     : 'me',

    password : 'secret',

    database : 'Database1'

});

app.put('/api/upload', function(req, res, next)

{

    connection.connect();

    doMultipleQueries(function(err)

    {

        connection.end();

    });          

};

The put request works perfectly fine, but calling it the second time, I get the following error

events.js:68

        throw arguments[1]; // Unhandled 'error' event

                       ^

Error: Cannot enqueue Handshake after invoking quit.

    at Protocol._validateEnqueue (/Users/anon/Desktop/project Web/node_modules/mysql/lib/protocol/Protocol.js:110:16)

Am I supposed to leave the connection open until the server dies?

UPDATE:
When I move the mysql.createConnection into the put request function like so:

var connection = null; 

app.put('/api/upload', function(req, res, next)

{

    connection = mysql.createConnection({

        host     : 'localhost',

        user     : 'me',

        password : 'secret',

        database : 'Database1'

    });

    connection.connect();

    doMultipleQueries(function(err)

    {

        connection.end();

    });          

};

It works fine. Does this mean connection.end() closes what mysql.createConnection created and cannot be reconnected?